January 30, 2009

Adult stem cells reset immune systems in MS patients

This comes to late for my sister Debby who has had MS for more than 30 years but it offers great hope for early phase MS.

Stem cells 'reset' immune system in MS patients in study.

Multiple sclerosis (MS) is an autoimmune disease that impairs movement and coordination, while causing muscle weakness, cognitive impairment, slurred speech and vision problems.
--
But in the decade or more after onset, MS is characterised by gradual but irreversible neurological impairment. There is no known cure.

In clinical trials, a team of scientists led by Richard Burt of Northwestern University in Chicago essentially rebuilt the immune system of 21 adults -- 11 women and 10 men -- who had failed to respond to standard drug treatments.

First they removed defective white blood cells that, rather than protecting the body, attacks the fatty sheath, called myelin, that protects the nervous system.

The immune systems were then replenished with so-called haemopoeitic stem cells -- extracted from the patient's bone marrow -- capable of giving rise to any form of mature blood cell.
--

The procedure "not only seems to prevent neurological progression, but also appears to reverse neurological disability," concluded the study, published in the British medical journal The Lancet.

Posted by Jill Fallon at January 30, 2009 10:25 AM | Permalink
Comments
Post a comment









Remember personal info?