May 15, 2017

New medical research and technology: Cure for baldness and greying, breast milk substance, anorexia partially genetic, UpnRide vertical wheelchair and more

Skin cell discovery could spell cure for baldness and grey hair:

Researchers were investigating how certain tumors form when they discovered the identity of the cells that produce hair and turn it grey.  The study found the protein called KROX20, more commonly associated with nerve development, turned on in skin cells that become the hair shaft. These hair precursor, or progenitor, cells then produce a protein called stem cell factor (SCF) which is essential for hair pigmentation.

Dr Lu Le, professor of Dermatology at UT Southwestern Medical Centre in Texas, said the chance discovery could lead to an effective treatment to cure baldness and stop greying.

Swedish scientists discover that breast milk contains a substance that kills cancer cells

Breast milk is being used to fight cancer after scientists accidentally discovered it contains a substance that kills tumor cells.Trials in patients with bladder cancer have already yielded promising results and researchers believe the compound breast milk contains – nicknamed Hamlet – will also help tackle bowel cancer and cervical cancer. They also say it homes in on cancer cells while leaving healthy cells unharmed – so it has none of the debilitating side effects of chemotherapy.

The substance attacks cancer cells in numerous ways – first evading the cell’s outer defenses, then targeting the ‘power station’ mitochondria and the ‘instruction manual’ nucleus. These actions cut off the cell’s energy source and ‘program’ it to commit suicide, in a process called apoptosis.

Professor Catharina Svanborg, who made the initial discovery, said last night: ‘There’s something magical about Hamlet’s ability to target tumor cells and kill them.’ She said human breast milk contained a protein called alpha-lactalbumin, which is transformed into a cancer-fighting agent when in the gut. An immunologist at Lund University in Sweden, she made the chance discovery that the substance kills tumor cells when working on antibiotics.

Early trials in patients with bladder cancer show those injected with Hamlet start shedding dead tumour cells in their urine within days. A full-scale trial pitting Hamlet against a placebo ‘dummy drug’ is now planned.

Anorexia is partly genetic and eating disorder risk could be passed on to children, study finds

An international collaboration of scientists found that many people who suffer from anorexia nervosa have mutated DNA on a particular chromosome.

Apple's watch really can save your live: Study finds its sensors can spot signs of a stroke with 97% accuracy

The Apple Watch has been found to detect a heart condition that affects some 2.7 million people in the US, a new study has revealed. By pairing the smartwatch's heart rate sensors with artificial intelligence, researchers developed an algorithm capable of distinguishing an irregular heartbeat, known as atrial fibrillation, from a normal heart rhythm - and with 97 percent accuracy. Atrial fibrillation, although easily treatable, has been difficult to diagnose.

CCM disease, a common hard-to-treat brain disease starts in the GUT, study reveals

Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures.  Tests on mice showed certain gut bacteria triggered the formation of clusters that cause these seizures. Looking at human models it seems the same is true for people. Currently there is not drug available to treat CCM. The only treatment option is surgical removal.

In 2016, Dr Mark Kahn, a professor of Cardiovascular Medicine, discovered the molecular mechanism in cells that underlies CCM formation. These studies identify an unexpected, direct link between the microbiome and a common cerebrovascular disease.'This suggests that treatments designed to block TLR4 signaling or alter the microbiome may be used to treat this disease,' Dr Kahn said.

Looks like a Segway, acts like a wheelchair

Introducing the UPnRIDE convertible wheelchair from the Israeli makers of the ReWalk robotic exoskeleton....UPnRIDE will enable many wheelchair users to be fully mobile in standing position anywhere, including in an urban environment.

As a category, the standing wheelchair is not a new product. These devices have been shown to improve circulation, elimination and bone density, and could also improve overall quality of life and independence among wheelchair users.  What’s different about the UPnRIDE?“The twist we bring here is the stabilization,” said says Oren Tamari, CEO of RehaMed Technologies.

A new laser imaging technique now allows for a real time look inside the the body of a small animal.

The technique, which uses light and ultrasound, provides enough resolution to see active organs, flowing blood, circulating melanoma cells and firing neural networks.  The researchers, based at the Duke University and The California Institute of Technology (Caltech), used a technique called 'single-impulse photoacoustic computed tomography (SIP-PACT)' to produce the images.

Posted by Jill Fallon at May 15, 2017 7:40 PM | Permalink